Includes part of Eastside and all lower valley districts. It is the third largest area of the city, behind east El Paso and central El Paso. Hawkins Road and Interstate 10 border the Mission Valley. This location is considered the oldest area of El Paso, dating back to the late 17th century when present-day Texas was under the rule of Nueva España (New Spain).
On April 30, 1598, the northward-bound Spanish conquistadors crossed large sand dunes about 27 miles south of present-day downtown El Paso. It is said that the expeditionaries and their horses ran toward the river, and two horses drank themselves to death. Don Juan de Oñate, a New Spain-born conquistador of Spanish parents, was an expedition leader who ordered a big feast north of the Río Grande in what is now San Elizario. This was the first documented and true Thanksgiving in North America. Oñate declared La Toma (taking possession), claiming all territory north of the Río Grande for King Philip II of Spain.
Some people in this area and its twin city across the river, Ciudad Juárez, are direct descendants of the Spaniards.